A facile synthesis of (carbazolyl)formamidines

作者：Meesala Ramu^*; Arshad Ahmad Saifuddin Mohamad; Mordi Mohd Nizam; Mansor Sharif Mahsufi

来源：Tetrahedron Letters, 2014, 55(51): 7023-7025.

DOI：10.1016/j.tetlet.2014.10.123

• N-(Carbazol-3-yl)acetamides
• N,N-Dimethylformamide
• POCl3
• (Carbazol-3-yl)formamidines
• Aminocarbazole

The reactions of N-(carbazol-3-yl)acetamides with N,N-dimethylformamide in the presence of phosphorus oxychloride (POCl3) at 90 degrees C gave the corresponding (carbazol-3-yl)formamidines in good yields. The method is compatible with a variety of functional groups.

• 出版日期2014-12-17