Different types of optic disc shape in patients with advanced open-angle glaucoma

作者：Nakazawa Toru^*; Fuse Nobuo; Omodaka Kazuko; Aizawa Naoko; Kuwahara Souichiro; Nishida Kohji

来源：Japanese Journal of Ophthalmology, 2010, 54(4): 291-295.

DOI：10.1007/s10384-010-0816-y

• advanced glaucoma
• disc type
• low vision
• myopia
• normal-tension glaucoma

To study the characteristics of patients with advanced open-angle glaucoma.
A hospital-based retrospective study was performed. Advanced glaucoma was defined as visual acuity of 0.3 or less, or mean deviation of -24 dB or less. First, we screened patients with advanced glaucoma and classified their glaucoma types. For patients with open-angle glaucoma (OAG), including both primary open-angle glaucoma (POAG) and normal-tension glaucoma (NTG), disc types were classified into four groups: focal ischemic (FI), myopic glaucomatous (MY), senile sclerotic (SS), and generalized cup enlargement (GE).
After checking the medical history of 750 glaucoma patients, we classified 141 (18.8%) as having the advanced stage of the disease. The proportion of patients with advanced OAG was 47% (28% POAG, 19% NTG). The classification of optic disc appearances in OAG patients showed that in patients with POAG the predominant disc type was GE (P = 0.0012) and in those with NTG it was MY (P < 0.0001).
In OAG patients in this study with severe glaucomatous damage, the predominant disc phenotype was GE in patients with POAG and MY in those with NTG.

• 出版日期2010-7