An efficient ligand-free ferric chloride catalyzed synthesis of annulated 1,4-thiazine-3-one derivatives

作者：Majumdar K C^*; Ghosh Debankan

来源：Tetrahedron Letters, 2014, 55(19): 3108-3110.

DOI：10.1016/j.tetlet.2014.04.005

• C-S coupling
• Ferric chloride
• Sodium sulfide
• 1,4-Thiazine-3-one

A straight forward route for the synthesis of coumarin-, quinolone-annulated 1,4-thiazine-3-one derivatives has been achieved by using sodium sulfide as the sulfur source and ferric chloride as catalyst in a ligand-free condition. The synthetic procedure is simple, inexpensive, and affords the products in good yields. This methodology is also applicable to naphthalene and benzene systems.

• 出版日期2014-5-7