A combined approach to patients with repeated IVF failures

作者：Orvieto Raoul^*; Meltcer Simion; Liberty Gad; Rabinson Jacob; Anteby Eyal Y; Nahum Ravit

来源：Fertility and Sterility, 2010, 94(6): 2462-2464.

DOI：10.1016/j.fertnstert.2010.03.057

• Repeated IVF failures
• ultrashort GnRH-agonist
• flexible multidose GnRH-antagonist
• COH
• endometrium
• local injury
• IVF outcome

In an attempt to evaluate the appropriate approach in patients with repeated IVF failures, we compared the stimulation characteristics of 19 cycles. This includes the combination of diagnostic hysteroscopy and endometrial sampling during oral contraceptive pill treatment, which precedes the ultrashort GnRH-ag/GnRH-ant protocol to the patients' previous failed IVF attempt. Patients undergoing the combined approach achieved an improved outcome with reasonable implantation and clinical pregnancy rates (25 and 42%, respectively). (Fertil Steril (R) 2010;94:2462-4.

• 出版日期2010-11