A highly regioselective sp(3) C-H amination of tertiary amides based on Fe(II) complex catalysts

作者：Mao Xuerong^*; Wu Yuanzhao; Jiang Xiaoxiang; Liu Xunhua; Cheng Yixiang; Zhu Chengjian

来源：RSC Advances, 2012, 2(17): 6733-6735.

DOI：10.1039/c2ra20707a

A highly regioselective sp(3) C-H amination of aryl amides with N-substituted pyrrolidin-2-ones has been developed with a catalyst Fe(II) complex with TBHP as a benign oxidant. This facile method can offer rapid access to the amination reaction of N-substituted pyrrolidin-2-ones in moderate to excellent yields.

• 出版日期2012
• 单位南京大学