Sexually transmitted infections and risk of prostate cancer: review of historical and emerging hypotheses

作者：Sutcliffe Siobhan^*

来源：Future Oncology, 2010, 6(8): 1289-1311.

DOI：10.2217/FON.10.95

• Chlamydia trachomatis
• gonorrhea
• herpesvirus
• human papillomavirus
• prostate cancer
• sexually transmitted infection
• syphilis
• Trichomonas vaginalis

Since the early 1950s when sexually transmitted infections (Sits) were first proposed as a possible risk factor for prostate cancer, numerous epidemiologic studies have been conducted. Initially, these studies were primarily small case-control studies with retrospective, self-reported assessments of a narrow range of Sits, typically either any Sits, or gonorrhea and syphilis. However, as new Sits have been discovered/recognized, new and better tests to detect histories of Sits have been developed, and new resources for prostate cancer research have been created, epidemiologic studies have expanded to include a wide range of Sits, and have moved towards more rigorous, prospective study designs and serological assessment of Sit histories. The results of these studies are reviewed and discussed, as well as possible new avenues of research, such as Trichomonas vaginalis infection and infections not typically considered to be sexually transmitted.

• 出版日期2010-8