A concise synthesis of (+)-botryolide-E and its C-7 epimer

作者：Liu, Xiaojing; Chen, Ruijiao; Duan, Feixia; Jia, Junhao; Zhou, Yuqin; Chen, Xiaochuan^*

来源：Tetrahedron Letters, 2017, 58(42): 3947-3950.

DOI：10.1016/j.tetlet.2017.08.057

• Botryolide-E
• Epimer
• Natural product
• Synthesis
• gamma-Lactone

The first synthesis of (+)-botryolide-E and its C-7 epimer has been achieved in 8 steps from o-Glucono-3lactone, and their antibiotic activities were also investigated preliminarily.

• 出版日期2017-10-18
• 单位四川大学; 济宁医学院