A numbers game underpins cytoplasmic mRNA transport

作者:Doyle Michael*; Kiebler Michael A
来源:Nature Cell Biology, 2012, 14(4): 333-335.
DOI:10.1038/ncb2475

摘要

Microtubule-based mRNA transport participates in the establishment of cell asymmetries. An in vitro reconstitution assay demonstrates that localization signals present in an mRNA influence motor copy number on single RNA molecule cargoes, ultimately leading to highly polarized distributions of transcripts.

  • 出版日期2012-4