Phosphine-catalyzed regioselective Michael addition to allenoates

作者:Gandi Vasudeva Rao; Lu Yixin
来源:Chemical communications, 2015, 51(90): 16188-16190.
DOI:10.1039/c5cc06197k

摘要

The first phosphine catalysed Michael addition of arylcyanoacetates to allenoates has been developed, and the beta-selective products with a quaternary center were obtained in excellent yields. This unusual regioselectivity may open new opportunities to access interesting molecular structures.

  • 出版日期2015