科研之友
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摘要
Six-membered chiral cyclic amines are important skeletal structures found in natural products as well as bioactive species. Asymmetric hydrogenation of six-membered N-heteroaromatic compounds is considered one of the most straightforward protocols for preparing six-membered chiral cyclic amines, because asymmetric hydrogenation is an atom economical reaction and applicable to industrial scales. In this review, we summarize the development of asymmetric hydrogenation of six-membered N-heteroaromatic compounds, such as pyridines, pyrazines, pyrimidines, and pyridones.
- 出版日期2017-1-25
