An enzymatic route to 5-deoxy-5-[F-18]fluoro-D-ribose, a [F-18]-fluorinated sugar for PET imaging

作者：Onega Mayca; Domarkas Juozas; Deng Hai; Schweiger Lutz F; Smith Timothy A D; Welch Andrew E; Plisson Christophe; Gee Antony D; O'Hagan David^*

来源：Chemical Communications, 2010, 46(1): 139-141.

DOI：10.1039/b919364b

An efficient two-step, one-pot, biotransformation involving the fluorinase enzyme is described for the synthesis of 5-deoxy-5[F-18]fluororibose, a novel [F-18]-fluorinated sugar suitable for positron emission tomography (PET) applications.

• 出版日期2010