A multiplex PCR for 11 X chromosome STR markers and population data from a Brazilian Amazon Region

作者：Ribeiro Rodrigues Elzemar Martins; das Neves Leite Fabio Pereira; Hutz Mara Helena; Ferreira Palha Teresinha de Jesus Brabo; Campos Ribeiro dos Santos Andrea Kely; Batista dos Santos Sidney Emanuel

来源：Forensic Science International-Genetics, 2008, 2(2): 154-158.

DOI：10.1016/j.fsigen.2007.10.179

• Amazon
• Multiplex PCR
• X-STR markers
• Population data
• Forensic genetic

The analysis of X-STR polymorphisms has received the attention of several researchers, mainly due to its applicability to the investigation of complex kinship cases. Although many X-STRs have been validated for forensic use, little is known about the variations of these polymorphisms in different populations of the world. The present work describes a new multiplex system that allows the simultaneous analysis of 11 X-STR markers, for use both in paternity determination and more complex forensic cases. The loci investigated include DXS9895, DXS7132, DXS6800, DXS9898, DXS6789, DXS7133, DXS7130, HPRTB, GATA31E08, DXS7423, and DXS10011. which together afford a power of discrimination in the order of 0.999999. In addition, this work presents the genotyping results obtained for a sample of 324 individuals (182 males and 142 females) from the admixed population of Belem, Para, located in the Brazilian Amazon Region.

• 出版日期2008-3