Dual Antiplatelet Therapy Dilemmas: Duration and Choice of Antiplatelets in Acute Coronary Syndromes

作者：Tomey Matthew; Mehran Roxana^*

来源：Current Cardiology Reports, 2013, 15(10): 405.

DOI：10.1007/s11886-013-0405-z

• Dual antiplatelet therapy
• Acute coronary syndromes
• Clopidogrel
• Prasugrel
• Ticagrelor
• Ischemia
• Bleeding
• Clinical prediction tool
• Platelet function testing
• Cost-effectiveness
• Therapeutic window

Dual antiplatelet therapy (DAPT) is a key component of therapy for acute coronary syndromes managed with and without percutaneous coronary intervention. Recent advances have given patients a wider variety of therapeutic options including the use of combinations of agents, dosing strategies, and durations of therapy. The optimal regimen minimizes thrombotic risk without increasing the risk of bleeding. Choosing the best therapy for each patient is an individualized dilemma that requires new, evidence-based tools to support regimen decision-making.

• 出版日期2013-10