A real-time colorimetric assay for label-free detection of microRNAs down to sub-femtomolar levels

作者:Shen Wei; Deng Huimin; Ren Yuqian; Gao Zhiqiang*
来源:Chemical communications, 2013, 49(43): 4959-4961.
DOI:10.1039/c3cc41565a

摘要

A real-time colorimetric assay utilizing gold nanoparticle networks and a duplex-specific nuclease (DSN) for label-free detection of microRNAs is proposed. Excellent sensitivity and selectivity were accomplished through the engagement of the DSN and a cumulative signal amplification process.

  • 出版日期2013