MRI T1 rho and T2 mapping for the assessment of articular cartilage changes in patients with medial knee osteoarthritis after hemicallotasis osteotomy

作者：Nishioka H^*; Nakamura E; Hirose J; Okamoto N; Yamabe S; Mizuta H

来源：Bone & Joint Research, 2016, 5(7): 294-300.

DOI：10.1302/2046-3758.57.BJR-2016-0057.R1

• T1 rho mapping
• T2 mapping
• Hemicallotasis osteotomy
• Cartilage

Objectives
The purpose of this study was to clarify the appearance of the reparative tissue on the articular surface and to analyse the properties of the reparative tissue after hemicallotasis osteotomy (HCO) using MRI T1 rho and T2 mapping.
Methods
Coronal T1 rho and T2 mapping and three-dimensional gradient-echo images were obtained from 20 subjects with medial knee osteoarthritis. We set the regions of interest (ROIs) on the full-thickness cartilage of the medial femoral condyle (MFC) and medial tibial plateau (MTP) of the knee and measured the cartilage thickness (mm) and T1 rho and T2 relaxation times (ms). Statistical analysis of time-dependent changes in the cartilage thickness and the T1 rho and T2 relaxation times was performed using one-way analysis of variance, and Scheffe's test was employed for post hoc multiple comparison.
Results
The cartilage-like repair tissue appeared on the cartilage surface of the medial compartment post-operatively, and the cartilage thickness showed a significant increase between the pre-operative and one-year post-operative time points (MFC; p = 0.003, MTP; p < 0.001). The T1 rho values of the cartilage-like repair tissue showed no difference over time, however, the T2 values showed a significant decrease between the pre-operative and one-year postoperative time points (MFC; p = 0.004, MTP; p = 0.040).
Conclusion
This study clarified that the fibrocartilage-like repair tissue appeared on the articular surface of the medial compartment after HCO as evidenced by MRI T1 rho and T2 mapping.

• 出版日期2016-7