An Expeditious Enantiospecific Total Synthesis of (-)-Crassalactone C

作者：Prasad Kavirayani R^*; Kumar S Mothish

来源：Synthesis, 2013, 45(6): 785-790.

DOI：10.1055/s-0032-1318303

• crassalactone C
• natural products
• stereoselective synthesis
• styryllactone

A concise and expeditious approach for the total synthesis of bioactive styryllactone (-)-crassalactone C is presented from tartaric acid. The main features of the synthesis include the desymmetrization of dimethylamide of tartaric acid and the effective use of cinnamoyl ester as a protecting group as well as a reactant in the ring-closing metathesis reaction.

• 出版日期2013-3