A millisecond micromixer via single-bubble-based acoustic streaming

作者：Ahmed Daniel; Mao Xiaole; Shi Jinjie; Juluri Bala Krishna; Huang Tony Jun^*

来源：Lab on a Chip, 2009, 9(18): 2738-2741.

DOI：10.1039/b903687c

We present ultra-fast homogeneous mixing inside a microfluidic channel via single-bubble- based acoustic streaming. The device operates by trapping an air bubble within a "horse-shoe'' structure located between two laminar flows inside a microchannel. Acoustic waves excite the trapped air bubble at its resonance frequency, resulting in acoustic streaming, which disrupts the laminar flows and triggers the two fluids to mix. Due to this technique's simple design, excellent mixing performance, and fast mixing speed (a few milliseconds), our single-bubble-based acoustic micromixer may prove useful for many biochemical studies and applications.

• 出版日期2009