Design and development of a dedicated portable gamma camera system for intra-operative imaging

作者：Kaviani Sanaz; Zeraatkar Navid; Sajedi Salar; Akbarzadeh Afshin; Gorjizadeh Nahid; Farahani Mohammad Hossein; Teimourian Behnoosh; Ghafarian Pardis; Sabet Hamid; Ay Mohammad Reza^*

来源：Physica Medica, 2016, 32(7): 889-897.

DOI：10.1016/j.ejmp.2016.06.004

• Sentinel lymph node (SLN)
• Lymphoscintigraphy
• SURGEOSIGHT-I
• Breast cancer
• Intra-operative gamma camera

Purpose: We developed a high performance portable gamma camera platform dedicated to identification of sentinel lymph nodes (SLNs) and radio-guided surgery for cancer patients. In this work, we present the performance characteristics of SURGEOSIGHT-I, the first version of this platform that can intraoperatively provide high-resolution images of the surveyed areas.
Methods: At the heart of this camera, there is a 43 x 43 array of pixelated sodium-activated cesium iodide (CsI(Na)) scintillation crystal with 1 x 1mm(2) pixel size and 5 mm thickness coupled to a Hamamatsu H8500 flat-panel multi-anode (64 channels) photomultiplier tube. The probe is equipped with a hexagonal parallel-hole lead collimator with 1.2 mm holes. The detector, collimator, and the associated front-end electronics are encapsulated in a common housing referred to as head.
Results: Our results show a count rate of similar to 41 kcps for 20% count loss. The extrinsic energy resolution was measured as 20.6% at 140 keV. The spatial resolution and the sensitivity of the system on the collimator surface was measured as 2.2 mm and 142 cps/MBq, respectively. In addition, the integral and differential uniformity, after uniformity correction, in useful field-of-view (UFOV) were measured 4.5% and 4.6%, respectively.
Conclusions: This system can be used for a number of clinical applications including SLN biopsy and radiopharmaceutical-guided surgery.

• 出版日期2016-7