New structures, chemical functions, and inhibitors for glycosyltransferases

作者：Roychoudhury Rajarshi; Pohl Nicola L B^*

来源：Current Opinion in Chemical Biology, 2010, 14(2): 168-173.

DOI：10.1016/j.cbpa.2010.01.013

Glycosyltransferases are key enzymes in a range of biological processes. The last two years have seen a new appreciation for the range of structural folds that can be adopted by this class of enzymes in addition to continued work in solving the structures of more varieties of these proteins, delineating their chemical function, and designing inhibitors of their catalytic function.

• 出版日期2010-4