Nickel-Catalyzed Intermolecular Insertion of Aryl Iodides to Nitriles: A Novel Method to Synthesize Arylketones

作者:Hsieh Jen Chieh*; Chen Yen Chung; Cheng An Yi; Tseng Hsiao Chun
来源:Organic Letters, 2012, 14(5): 1282-1285.
DOI:10.1021/ol3001531

摘要

A novel procedure for the NiCl2(DME)/dppp/Zn system catalyzed intermolecular insertion of aryl iodides to nitriles was developed, which afforded variously substituted arylketone derivatives in moderate to good yields with tolerance of a wide variety of functional groups.

  • 出版日期2012-3-2