Arterite de Takayasu: aspectos cl赤nicos e terap那uticos em 36 pacientes

作者:Panico; Marilia Duarte Brando; Spichler; Ethel Stambovsky; Rodrigues; Leandro Cordeiro Dias; Oliveira; Fernando; Buchatsky; Daniel; Porto; Carmen; Alves; Marcia Ribeiro; Spichler; David
来源:Jornal Vascular Brasileiro, 2008.
DOI:10.1590/S1677-54492008000200006

摘要

background: takayasu arteritis is a chronic vasculitis often with delayed diagnosis due to the nonspecific presentation of clinical symptoms in its initial phase. treatment includes imunosuppression drugs. surgical treatment, when necessary, should be avoided in the acute phase. objective: to describe clinical, laboratory and vascular findings in takayasu%26apos;s arteritis from 1977 through 2006. methods: the sample was comprised of 36 patients (10 caucasians, 35 women), mean age of 31.7 (㊣13.7) years, and significant prevalence in the forth decade (p 60 mm in 50% of the sample (p 3 mm (41.6%), 1.7 (19.4%), 1.2 (8.37%), and %26lt; 1.2 mm (30.50%) (p %26lt; 0.005). glucocorticoids were used in 61%, azathioprine in 16.6%, and azathioprine combined with cyclophosphamide in 8.3%. surgical and endovascular procedures were performed in 30.5%. two patients died due to cardiovascular diseases. conclusions: carotid intima-media thickness, pcr, and esr are important markers for the follow-up of takayasu%26apos;s arteritis. delay in diagnosis is an important issue for takayasu%26apos;s progression, since it may reduce morbidity and mortality r

  • 出版日期2008

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