Analogical China Map Self-assembled from Single-Stranded DNA Tiles

作者:Wang Yanfeng; Ma Xin; Li Mengmeng; Cui Guangzhao*
来源:10th International Conference on Bio-Inspired Computing - Theories and Applications (BIC-TA), 2015-09-25 to 2015-09-28.
DOI:10.1007/978-3-662-49014-3_38

摘要

Single-stranded DNA tile (SST) assembly provides a simple, modular and robust framework for constructing nanostructures with prescribed shapes from short synthetic DNA strands. Here we presents a nanoscale DNA structure of analogical China map which is constructed by a number of SSTs. The constructing nanostructure is roughly 98nmx67nm in diameter with a spatial resolution of 3 nmx7nm. The pattern appeared in atomic force microscopy (AFM) conforms to the pre-designed shape of Chinese map with the approximately expected dimensions, and AFM images of the field selected randomly from the mica give an 11% assembly yield. Through this research, the capability of constructing complicated two-dimensional shapes by SST and the controllability of the internal array are fully vindicated.

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