Lay health worker led intervention for depressive and anxiety disorders in India: impact on clinical and disability outcomes over 12 months

作者：Patel Vikram^*; Weiss Helen A; Chowdhary Neerja; Naik Smita; Pednekar Sulochana; Chatterjee Sudipto; Bhat Bhargav; Araya Ricardo; King Michael; Simon Gregory; Verdeli Helena; Kirkwood Betty R

来源：The British Journal of Psychiatry, 2011, 199(6): 459-466.

DOI：10.1192/bjp.bp.111.092155

Background
Depressive and anxiety disorders (common mental disorders) are the most common psychiatric condition encountered in primary healthcare.
Aims
To test the effectiveness of an intervention led by lay health counsellors in primary care settings (the MANAS intervention) to improve the outcomes of people with common mental disorders.
Method
Twenty-four primary care facilities (12 public, 12 private) in Goa (India) were randomised to provide either collaborative stepped care or enhanced usual care to adults who screened positive for common mental disorders. Participants were assessed at 2, 6 and 12 months for presence of ICD-10 common mental disorders, the severity of symptoms of depression and anxiety, suicidal behaviour and disability levels. All analyses were intention to treat and carried out separately for private and public facilities and adjusted for the design. The trial has been registered with clinicaltrials.gov (NCT00446407).
Results
A total of 2796 participants were recruited. In public facilities, the intervention was consistently associated with strong beneficial effects over the 12 months on all outcomes. There was a 30% decrease in the prevalence of common mental disorders among those with baseline ICD-10 diagnoses (risk ratio (RR)=0.70, 95% CI 0.53-0.92); and a similar effect among the subgroup of participants with depression (RR=0.76, 95% CI 0.59-0.98). In contrast, there was little evidence of impact of the intervention on any outcome among participants attending private facilities.
Conclusions
Trained lay counsellors working within a collaborative-care model can reduce prevalence of common mental disorders, suicidal behaviour, psychological morbidity and disability days among those attending public primary care facilities.

• 出版日期2011-12
• 单位南宁师范大学