Association of the candidate gene SLC1A1 and obsessive-compulsive disorder in Han Chinese Population

作者：Wu, Haisu; Wang, Xuemei; Yu, Shunying; Wang, Dongxiang; Chen, Jianhua; Jiang, Kaida; Zhu, Liping; Xiao, Zeping^*; Fralick, Drew

来源：Psychiatry Research, 2013, 209(3): 737-739.

DOI：10.1016/j.psychres.2012.12.016

• Obsessive-compulsive disorder
• Haplotype
• Glutamate transporter gene

This case-control study enrolled 578 obsessive-compulsive disorder (OCD) patients and 649 controls and genotyped rs10491734, rs2228622, rs301430 and rs301443 to replicate association of the SLC1A1 gene with OCD in ethnic Han Chinese. The G-A-C-G and G-G-T-C haplotypes were found to be significantly associated with OCD in overall samples, male samples and female samples.

• 出版日期2013-10-30
• 单位上海交通大学; 上海市精神卫生中心