摘要
In this study nickel ferrite magnetic nanoparticles were applied as an efficient and reusable catalyst in the four-component synthesis of substituted pyrroles under neat conditions. The reaction was conducted using various amounts of catalyst at different temperatures and finally, application of 5 mol% of catalyst at 100 degrees C was determined as the optimum reaction condition. Results showed that nickel ferrite nanoparticles could catalyze the reaction at relatively short times (3-4 h) with high to excellent yields (70-96%). The catalyst could be recovered easily using an external magnetic field and reused nine times without any significant activity lost.
- 出版日期2015