Aerobic Oxidative Kinetic Resolution of Secondary Alcohols with Naphthoxide-Bound Iron(salan) Complex

作者：Kunisu Takashi; Oguma Takuya; Katsuki Tsutomu^*

来源：Journal of the American Chemical Society, 2011, 133(33): 12937-12939.

DOI：10.1021/ja204426s

The first general method for iron-catalyzed aerobic oxidative kinetic resolution of secondary alcohols was achieved with good to high enantiomeric differentiation (k(rel) = 7-50). Although iron(salan) complex 1 does not catalyze alcohol oxidation, the naphthoxide-bound iron(salan) complex does.

• 出版日期2011-8-24