A luminescent turn-up metal-organic framework sensor for tryptophan based on singlet-singlet Forster energy transfer

作者：Zhang, Jun; Huang, Yike; Yue, Dan; Cui, Yuanjing^*; Yang, Yu; Qian, Guodong^*

来源：Journal of Materials Chemistry B, 2018, 6(31): 5174-5180.

DOI：10.1039/c8tb01592a

• AMINO-ACIDS
• MOF
• FLUORESCENCE
• POLYMER
• COMPOSITE
• TARGET
• FILM

A water stable metal-organic framework, ZJU-108, was designed and successfully synthesized as a luminescent turn-up sensor, and it can discriminate tryptophan from other natural amino acids in aqueous solution. Because of the apparent lower singlet level of tryptophan compared with other amino acids, the singlet-singlet Forster energy transfer mechanism was applied to design a luminescent sensor. As a result, a selective MOF sensor for tryptophan was realized by choosing the ligand with the appropriate singlet energy level. As expected, ZJU-108 shows an excellent luminescence enhancement response to tryptophan over other natural amino acids with a detection limit of 42.9 nM. This work presents a new insight for designing turn-up MOF sensors and demonstrates the potential of ZJU-108 as a luminescent probe for the detection of tryptophan.

• 单位
  硅材料国家重点实验室; 浙江大学