Utilizing Palladium-Stabilized Zwitterions for the Construction of N-Heterocycles

作者:Allen Benjamin D W; Lakeland Christopher P; Harrity Joseph P A
来源:Chemistry - A European Journal, 2017, 23(56): 13830-13857.
DOI:10.1002/chem.201702486

摘要

<jats:title>Abstract</jats:title><jats:p>Pd catalysis provides a convenient method for the generation of zwitterionic intermediates that offer significant opportunities for the synthesis of functionalized heterocycles. The combination of electrophilic π‐allyl Pd fragments and C‐, N‐ and O‐centered nucleophiles allows these intermediates to react with readily available substrates to furnish a range of high value products with control of chemo‐, regio‐ and stereo‐selectivity.</jats:p>

  • 出版日期2017-10-9