Tumescent Anesthesia in Skin- and Nipple-sparing Mastectomy: Results of a Prospective Clinical Study

作者：Gipponi Marco^*; Baldelli Ilaria; Atzori Giulia; Fregatti Piero; Murelli Federica; Pesce Marianna; Margarino Cecilia; Depaoli Francesca; Friedman Daniele

来源：Anticancer Research, 2017, 37(1): 349-352.

DOI：10.21873/anticanres.11328

• Breast cancer
• breast reconstruction
• tumescent anesthesia

Background: The tumescent mastectomy technique has been used to facilitate dissection of subcutaneous tissue and mammary gland in order to reduce intraoperative bleeding and speed the operation. Patients and Methods: A prospective clinical study was performed on 30 female patients undergoing immediate breast reconstructions after skin-sparing mastectomy (SSM) or nipple-sparing mastectomy (NSM) in order to assess early postoperative complications, pain, and final esthetic outcome of skin flaps related to tumescent anesthesia (TA). Results: TA significantly speeded-up the operative procedure (131 +/- 49.99 vs. 180.5 +/- 67.15 min; p=0.03) achieving less skin damage compared to patients who did not have TA (p=0.045); moreover, no significant difference occurred with regard to the length of in-hospital stay and overall lymphatic drainage. Conclusion: The length of the operation as well as the final cosmetic outcome of skin flaps was significantly improved due to TA, with no appreciable side-effects.

• 出版日期2017-1