Deteriorating tactile sensation in patients with hand syndromes associated with diabetes: A two-year observational study

作者：Redmond Christine L^*; Bain Gregory I; Laslett Laura L; McNeil Julian D

来源：Journal of Diabetes and Its Complications, 2012, 26(4): 313-318.

DOI：10.1016/j.jdiacomp.2012.04.009

• Diabetes
• Carpal tunnel syndrome
• Trigger finger
• Touch perception
• Dexterity

Aims: To observe the natural history of hand function during a two-year period in participants with hand syndromes associated with diabetes and to determine factors related to changing function. %26lt;br%26gt;Methods: Hand function was measured over three annual visits using Disability of the Arm, Shoulder and Hand (DASH) and SF-36v2 questionnaires, grip strength, light touch and 9-hole peg tests. Light touch was tested with WEST monofilaments at 7 sites on the hand (score 35 to 0). Data were analyzed using repeated-measures ANOVA, Spearman%26apos;s correlation, and Wilcoxon signed-rank tests. %26lt;br%26gt;Results: Participants (n = 60) were aged 61 +/- 10.5 years, 57% female, diagnosed with diabetes and at least one of four associated hand disorders. Presentations of carpal tunnel syndrome, or past release (n =27, 45%) and trigger finger (n = 24, 40%) were common. Tactile sensation was reduced during the two-year period (median, range; 30 months, 25-40 months). Initial median (inter-quartile range) scores for the dominant hand of 25.5 (22-28.5) were reduced to 23 (21.5-27). This sensory loss was weakly associated with HbA1c (r = 0.30, p = 0.05) and occurred predominantly in participants with trigger finger (p = 0.05). %26lt;br%26gt;Conclusions: Light touch perception was reduced in longstanding diabetic hand syndromes. Tactile abnormalities that were detected by clinical examination progressed during a two year period and were related to metabolic control and musculoskeletal diagnosis.

• 出版日期2012-8