Microbial Biotransformation of 16 alpha,17-Epoxy-ent-kaurane-19-oic acid by Beauveria sulfurescens ATCC 7159-F

作者:Furtado Ricardo A; Gunaherath G M Kamal B; Bastos Jairo K*; Gunatilaka A A Leslie
来源:Natural Product Communications, 2013, 8(8): 1041-1044.
DOI:10.1177/1934578x1300800802

摘要

Biotransformation of 16 alpha,17-epoxy-ent-kaurane-19-oic acid (1) by Beauveria sulfurescens ATCC 7159-F led to the production of a new ent-kaurane diterpenoid, 7 beta,17-dihydroxy-ent-kaur-15-en-19-oic acid (7), and four other ent-kauranes (8 - 11), all of which were identified as their methyl esters. Compounds 9 and 10 were found to be new stereoisomers. Structures of these were established by the extensive usage of their spectroscopic characteristics.

  • 出版日期2013-8