Detection of Mycoplasma genitalium from male primary urine specimens: an epidemiologic dichotomy with Trichomonas vaginalis

作者：Napierala Maureen; Munson Erik^*; Wenten David; Phipps Paula; Gremminger Roger; Schuknecht Mary Kay; Munson Kimber L; Boyd Vivian; Hamer Deb; Schell Ronald F; Hryciuk Jeanne E

来源：Diagnostic Microbiology and Infectious Disease, 2015, 82(3): 194-198.

DOI：10.1016/j.diagmicrobio.2015.03.016

• Mycoplasma genitalium
• Transcription-mediated amplification
• Sexually transmitted infection
• Males
• Trichomonas vaginalis

A total of 2750 male urines subjected to a transcription-mediated amplification (TMA)-based Mycoplasma genitalium assay yielded 188 positive results (6.84%). This rate was similar to Chlamydia trachomatis (6.87%; P = 0.96) and greater than Neisseria gonorrhoeae (4.0%) and Trichomonas vaginalis (2.3%; P < 0.0002). Mean age of M. genitalium-infected males (30.8) was similar to N. gonorrhoeae (P = 0.78) but less than T. vaginalis (mean, 41.6; P < 0.0001). A total of 266 STI clinic encounters had at least 1 sexually transmitted infection (STI); 36.5% of these encounters had sole detection of M. genitalium (P <= 0.009 versus sole detection of other STI agents). In 209 community encounters with at least 1 STI, 22.0% exhibited sole detection of M. genitalium (P = 0.0007 versus sole M. genitalium detection in STI clinic males), while 18.7% had sole detection of T. vaginalis (P < 0.0002 versus detection in STI clinic males). TMA-based M. genitalium screening identifies additional cases of nongonococcal urethritis.

• 出版日期2015-7