An efficient cascade synthesis of substituted 6,9-dihydro-1H-pyrazolo[3,4-f]quinoline-8-carbonitriles

作者：Li, Hong-Lei; Chen, Juan; Chen, Dong-Sheng; Shi, Pan; Liu, Jia-Yan^*

来源：Heterocyclic Communications, 2018, 24(5): 279-283.

DOI：10.1515/hc-2018-0131

• catalyst-free
• multi-component domino reactions
• pyrazoloquinoline

The synthesis of pyrazolo[3,4-f]quinoline-8-carbonitriles 4a-h and 6a-k involves the reaction of an aromatic aldehyde, 1H-indazol-6-amine and 3-(1H-indol-3-yl)-3-oxopropanenitrile or 3-oxo-3-arylpropanenitrile in ethanol under mild conditions.

• 出版日期2018-10
• 单位南京医科大学