A mild and efficient method for chemoselective silylation of alcohols using hexamethyldisilazane in the presence of silica chloride

作者：Shirini F^*; Zolfigol MA; Mohammadi K

来源：Phosphorus, Sulfur, and Silicon and the Related Elements, 2003, 178(7): 1567-1570.

DOI：10.1080/10426500390212979

• alcohol
• chemoselective
• hexamethyldisilazane
• silica chloride
• silyl ether

Reaction of alcohols with hexamethyldisilazane in the presence of silica chloride provides efficiently the corresponding trimethylsilyl ethers. This system discriminates absolutely amines and thiols from alcohols.

• 出版日期2003-7