科研之友
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摘要
A highly efficient solvent-free and simple one-pot approach for the synthesis of 4-hydroxythiazolidine-2-thione is described. The reaction of primary amines and carbon disulfide in the presence of 2-chloroacetaldehyde afforded the title compounds in high yields. [GRAPHICS] . R: Substituted benzyl, Alkyl, 2-Hydroxyethyl (86-90%)
- 出版日期2014-8
