Detection of chemical interfaces in coherent anti-Stokes Raman scattering microscopy: D-CARS. II. Arbitrary interfaces

作者：Gachet David; Rigneault Herve^*

来源：Journal of the Optical Society of America A-Optics Image Science and Vision, 2011, 28(12): 2531-2539.

DOI：10.1364/JOSAA.28.002531

We address the general problem of detecting chemical interfaces arbitrarily oriented in space in coherent anti-Stokes Raman scattering (CARS) microscopy. Such a task is accomplished by using a beam reversal scheme, as recently demonstrated experimentally [J. Biomed. Opt. 16, 086006 (2011)]. We develop a full vectorial theoretical analysis of the situation and show that transverse chemical interfaces are readily highlighted without special care in the CARS signal detection. In addition, a finer analysis reveals that adequate angular analysis of the CARS far-field radiation pattern enables the detection of axial interfaces. Background-free CARS microscopy and spectroscopy are thus achievable through the combined application of excitation beam reversal and angular analysis of the CARS far-field radiation pattern. This differential CARS (D-CARS) technique is relevant for fast detection of interfaces between molecularly different media.

• 出版日期2011-12