Molded nanowell electrodes for site-selective single liposome arrays

作者:Kim Pinam; Lee Bong Kuk; Lee Hea Yeon*; Kawai Tomoji; Suh Kahp Y
来源:Advanced Materials, 2008, 20(1): 31-+.
DOI:10.1002/adma.200700570

摘要

We present a nanowell (NW)-based biosensing platform for electrochemically detecting biological reactions on the level of single lipid vesicle. The NW geometry of a gently-sloped vertical wall is found to be optimal for selective deposition of single liposomes without capillary resistances. Also, the use of a hydrophilic, non-biofouling PEG copolymer is essential to provide distinctively separated FLV arrays without nonspecific adsorption.

  • 出版日期2008-1-7