Asymmetric henry reaction catalyzed by chiral schiff base

作者：Ran, De-qiang; Shen, Tian-hua; Zhou, Xiao-cong; Li, Jun-qi; Cui, Fu-na; Ma, Chun-an; Song, Qing-bao^*

来源：Russian Journal of Organic Chemistry, 2013, 49(6): 849-852.

DOI：10.1134/S1070428013060080

• ALPHA-HYDROXY ESTERS
• NITROALDOL REACTIONS
• COMPLEXES
• LIGANDS
• BIS(THIAZOLINE)
• BIS(OXAZOLINE)

Four chiral Schiff bases were synthesized conveniently from chiral amino alcohol and 2-hydroxynaphthalene-1-carbaldehyde. These ligands were used to catalyze the addition of nitroalkanes to aldehydes under ambient conditions in good yields with up to 91% ee.

• 出版日期2013-6
• 单位浙江工业大学