A New Catalyst-Free Synthesis of 2,3-Dicarboxylic Ester Quinoline Derivatives

作者:Wang, Bin; Ye, Wenbo; Yan, Zicong; Wan, Changfeng*; Hou, Haoqing; Wang, Zhiyong
来源:Chinese Journal of Organic Chemistry, 2018, 38(2): 504-508.
DOI:10.6023/cjoc201708054

摘要

A high efficient method for the synthesis of 2,3-dicarboxylic ester quinoline derivatives which employed o-amino diphenyl methylone derivatives and acetylenedicarboxylic esters as the reaction substrates was developed. This method possessed the character of catalyst-free and mild reaction conditions. Proposed mechanism was also studied according to the reaction result.