Are Beta Blockers New Potential Anticancer Agents?

作者:Akbar Shahid*; Alsharidah Mansour Saleh
来源:Asian Pacific Journal of Cancer Prevention, 2014, 15(22): 9567-9574.
DOI:10.7314/APJCP.2014.15.22.9567

摘要

beta-Blockers have been one of the most widely used and versatile drugs for the past half a century. A new potential for their use as anti-cancer drugs has emerged in the past few years. Various retrospective case control studies have been suggestive that use of beta-blockers before the diagnosis of cancer could have preventive and protective effects against non-small cell lung carcinoma, melanoma, and breast, pancreatic and prostate cancers. Experimental and clinical observations are still inconclusive with some inconsistent findings. However, indications are pointing toward a positive role of some beta-blockers against certain forms of cancers. This mini review is an effort to present the up to date published results of case-control studies and experimental findings.

  • 出版日期2014