Multifunctional gold nanocomposites designed for targeted CT/MR/optical trimodal imaging of human non-small cell lung cancer cells

作者：Chen, Jingwen; Sun, Yingqi; Chen, Qian; Wang, Le; Wang, Suhe; Tang, Yun^*; Shi, Xiangyang^*; Wang, Han^*

来源：Nanoscale, 2016, 8(28): 13568-13573.

DOI：10.1039/c6nr03143a

• IRON-OXIDE NANOPARTICLES
• IN-VIVO
• MAGNETIC-RESONANCE
• CONTRAST AGENT
• PHOTOTHERMAL THERAPY
• NANOMEDICINE
• TUMORS
• MRI
• NANOSTRUCTURES
• NANOPROBES

Multifunctional gold nanocomposites, which were designed as dendrimer-entrapped gold nanoparticles functionalized with gadolinium, cyanine dye (Cy5.5), and folic acid, were synthesized to be used as the first dendrimer-based clinical nanoprobes for targeted X-ray computed tomography/magnetic resonance/optical trimodal imaging in vitro and in vivo of human non-small cell cancer cells.

• 出版日期2016
• 单位东华大学; 河北医科大学; 复旦大学; 上海交通大学; 上海中医药大学