Are circRNAs involved in cancer pathogenesis?

作者:Croce Carlo M*
来源:Nature Reviews Clinical Oncology, 2016, 13(11): 658-U21.
DOI:10.1038/nrclinonc.2016.113

摘要

In a paper published recently in Cell, Guarnerio et al. suggest that circular RNAs derived from cancer-associated chromosomal translocations have an oncogenic role; however, the experimental approach that the authors used was inadequate to generate sufficient evidence to prove this role, calling their study into question.

  • 出版日期2016-11