Association between diabetic retinopathy and subclinical atherosclerosis in China: Results from a community-based study

作者：Liu, Yu; Teng, Xiangyu; Zhang, Wei; Zhang, Ruifeng; Liu, Wei^*

来源：Diabetes and Vascular Disease Research, 2015, 12(5): 366-372.

DOI：10.1177/1479164115591744

• Diabetic retinopathy
• subclinical atherosclerosis
• type 2 diabetes

Purpose: To evaluate the association of diabetic retinopathy with subclinical atherosclerosis in middle-aged and elderly Chinese with type 2 diabetes. @@@ Methods: A cross-sectional community-based study was performed among 1607 patients aged 40years or older in Shanghai. Non-mydriatic digital fundus photography examination was used in diabetic retinopathy detection. Presence of elevated carotid intima-media thickness or carotid plaque was defined as subclinical atherosclerosis. @@@ Results: The prevalence of diabetic retinopathy was 15.1% in total patients. Patients with diabetic retinopathy were more likely to have elevated carotid intima-media thickness, carotid plaque and subclinical atherosclerosis than those without diabetic retinopathy (37.9% vs 30.7%, 57.6% vs 49.6% and 64.6% vs 57.1%, respectively). The presence of diabetic retinopathy was significantly associated with increased odds of subclinical atherosclerosis (odds ratio=1.93, 95% confidence interval=1.03-3.60) after full adjustments. @@@ Conclusion: The presence of diabetic retinopathy was significantly associated with subclinical atherosclerosis in middle-aged and elderly patients with type 2 diabetics in China.

• 出版日期2015-9
• 单位上海交通大学