A randomised controlled trial of cognitive behaviour therapy for psychosis in a routine clinical service

作者：Peters E^*; Landau S; McCrone P; Cooke M; Fisher P; Steel C; Evans R; Carswell K; Dawson K; Williams S; Howard A; Kuipers E

来源：Acta Psychiatrica Scandinavica, 2010, 122(4): 302-318.

DOI：10.1111/j.1600-0447.2010.01572.x

• cognitive functioning
• psychology
• psychoses
• randomised controlled trial
• schizophrenia

Objective:
To evaluate cognitive behaviour therapy for psychosis (CBTp) delivered by non-expert therapists, using CBT relevant measures.
Method:
Participants (N = 74) were randomised into immediate therapy or waiting list control groups. The therapy group was offered 6 months of therapy and followed up 3 months later. The waiting list group received therapy after waiting 9 months (becoming the delayed therapy group).
Results:
Depression improved in the combined therapy group at both the end of therapy and follow-up. Other significant effects were found in only one of the two therapy groups (positive symptoms; cognitive flexibility; uncontrollability of thoughts) or one of the two time points (end of therapy: general symptoms, anxiety, suicidal ideation, social functioning, resistance to voices; follow-up: power beliefs about voices, negative symptoms). There was no difference in costs between the groups.
Conclusion:
The only robust improvement was in depression. Nevertheless, there were further encouraging but modest improvements in both emotional and cognitive variables, in addition to psychotic symptoms.

• 出版日期2010-10