Air Pollution and the Risk of Birth Defects in Anqing City, China

作者：Yao, Cijiang; Chen, Yanyan; Zhu, Xiaoxia; Liu, Ying; Zhang, Jian; Hou, Lijuan; Xu, Yachun; Zhang, Chao; Cao, Jiyu^*

来源：Journal of Occupational and Environmental Medicine, 2016, 58(4): E124-E127.

DOI：10.1097/JOM.0000000000000676

• SAN-JOAQUIN VALLEY
• CONGENITAL-ANOMALIES
• PREGNANCY OUTCOMES
• TRAFFIC EXPOSURES
• MATERNAL EXPOSURE
• COUNTY
• ASSOCIATIONS
• BRINDISI
• COHORT
• HEALTH

Objective: This study aimed to explore evidence for the influence of air pollution on the risk of birth defects in China and contribute to establish prevention strategies. Methods: We conducted a retrospective cohort study in Anqing city, Eastern China, from 2010 to 2012. Binary logistic regression models were used to estimate odds ratios (ORs) per 10 mu g/m(3) change for SO2, NO2, and PM10. Results: For continuous exposure to SO2 (10 mu g/m(3) increase), the adjusted OR for birth defects is 1.20 [95% confidence interval (95% CI) 1.09 to 1.29] in the preconception. A 10 mu g/m(3) increase in SO2 (adjusted OR 1.26, 95% CI 1.15 to 1.36) during the second trimester is strongly associated with birth defects. No associations have been observed for NO2 and PM10. Conclusion: The results suggested that exposure to ambient SO2 during pregnancy may increase the risk of birth defects.

• 出版日期2016-4
• 单位安徽医科大学