A sensitive electrochemical sensor with sulfonated graphene sheets/oxygen-functionalized multi-walled carbon nanotubes modified electrode for the detection of clenbuterol

作者：Zhai, Haiyun^*; Liu, Zhenping; Chen, Zuanguang; Liang, Zhixian; Su, Zihao; Wang, Shumei

来源：Sensors and Actuators B: Chemical , 2015, 210: 483-490.

DOI：10.1016/j.snb.2014.12.121

• Sulfonated graphene sheets
• Oxygen-functionalized multi-walled carbon nanotubes
• Clenbuterol
• Hybrid nanomaterials
• Electrocatalyst

A novel electrochemical sensor was designed to determine clenbuterol by using a new hybrid nanomaterials of water-dispersible sulfonated graphene sheets (SGSs) and oxygen-functionalized multi-walled carbon nanotubes (MWCNTs-COOH) modified glass carbon electrode (GCE). The pi-pi stacking interaction between SGSs and MWCNTs-COOH was verified by UV-vis spectroscopy, fourier transform-infrared spectroscopy and scanning electron microscopy. The anodic peak current (Ipa) of clenbuterol at the GCE modified with SGSs/MWCNTs-COOH was much higher than those at the bare GCE, SGSs/GCE and MWCNTs-COOH/GCE due to the synergistic effect of the modified nanomaterials. Differential pulse voltammetry disclosed a good linear relationship between Ipa and concentrations of clenbuterol (0.01-5.0 mu M), with the detection limit of 4.6 nM. Finally, the modified electrode was successfully used to determine clenbuterol in liver samples.

• 出版日期2015-4
• 单位中山大学; 广东药科大学