Asymmetric Alkynylative Ring Opening Reaction of Oxabenzonorbornadienes Promoted by Palladium/Silver Cocatalytic System

作者：Liu, Shanshan; Li, Sifeng; Chen, Hualei; Yang, Qingjing; Xu, Jianbin; Zhou, Yongyun; Yuan, Minglong; Zeng, Weimin; Fan, Baomin^*

来源：Advanced Synthesis & Catalysis, 2014, 356(14-15): 2960-2964.

DOI：10.1002/adsc.201301047

• asymmetric synthesis
• catalysis
• oxabenzonorbornadienes
• ring opening reaction
• terminal alkynes

The combination of palladium(II) acetate/(R)-xylyl-Phanephos and silver triflate (Pd: Ag=1:1) was found to be an efficient catalytic system for the asymmetric ring opening reactions of oxabenzonorbornadienes with terminal alkynes. The products were typically afforded in good yields (up to 95% yield) and with high enantioselectivities (up to 99% ee).

• 出版日期2014-10-13
• 单位云南民族大学