A Mouse Following in the Footsteps of Human Prehistory

作者：Vohr Samuel H; Green Richard E^*

来源：Cell, 2013, 152(4): 667-668.

DOI：10.1016/j.cell.2013.01.039

One of the strongest signals of positive selection in humans surrounds the V370A variant of Ectodysplasin A receptor (EDAR). However, its phenotypic consequences and impetus for selection are not well understood. Kamberov et al. nail down when it originated and, using transgenic mice, delineate its phenotypic impacts.

• 出版日期2013-2-14