An estimator for local analysis of genome based on the minimal absent word

作者:Yang, Lianping; Zhang, Xiangde*; Fu, Haoyue; Yang, Chenhui
来源:Journal of Theoretical Biology, 2016, 395: 23-30.
DOI:10.1016/j.jtbi.2016.01.023

摘要

This study presents an alternative alignment-free relative feature analysis method based on the minimal absent word, which has potential advantages over the local alignment method in local analysis. Smooth local-analysis-curve and similarity-distribution are constructed for a fast, efficient, and visual comparison. Moreover, when the multi-sequence-comparison is needed, the local-analysis-curves can illustrate some interesting zones.