An outbreak of carbapenem-resistant Acinetobacter baumannii producing OXA-23 carbapenemase in western China

作者:Zong, Zhiyong; Lue, Xiaoju; Valenzuela, Jubelle K.; Partridge, Sally R.; Iredell, Jon*
来源:International Journal of Antimicrobial Agents, 2008, 31(1): 50-54.
DOI:10.1016/j.ijantimicag.2007.08.019

摘要

Twenty-two non-repetitive carbapenem-resistant Acinetobacter baumannii isolates were obtained from Intensive Care Unit patients. All of the isolates carried bla(OXA-23), bla(OXA-66), a novel cephalosporinase-encoding gene (bla(ADC-25)) and a class 1 integron with an aacCI-orfP-orfQ-aadAIa cassette array and had identical enterobacterial repetitive intergenic consensus (ERIC) profiles. ISAba1 was found upstream of bla(OXA-23), but was not associated with bla(OXA-66) or b/a(ADC-25).